Objective: Osteoarthritis is one of the most com- mon chronic conditions leading to disability among older people (age 60+ years).Knee osteoarthritis has a significant impact on daily functioning.Pain, stiffness, reduced strength, changes in posture, and reduced knee stability may result in reduced mobility.The aim of this study is to evaluate the
ABSTRACT The symbiosis between the squid Euprymna scolopes and its luminous symbiont, Vibrio fischeri, is characterized by daily transcriptional rhythms in both partners and daily fluctuations in symbiont luminescence.In this study, we sought to determine whether symbionts affect host transcriptional rhythms.We identified two transcripts in host ti
BackgroundScrub typhus, caused by Orientia tsutsugamushi infection, is one of the main causes of febrile illness in the Asia-Pacific region.Although cell-mediated immunity plays an important role in protection, little is known about the phenotypic changes and dynamics of leukocytes in scrub typhus patients.Methodology/principal findingsTo reveal th
Abstract Background Multiple clinical trials to assess the efficacy of AAV-directed gene transfer in participants with Duchenne muscular dystrophy (DMD) are ongoing.The success of these trials currently relies on standard functional outcome measures that may exhibit variability within and between participants, rendering their use as sole measures o
A successful posterior cruciate ligament (PCL) reconstruction depends on multiple factors.Various techniques have been described for PCL reconstruction.Despite the constant evolution of reconstructive techniques, 26% of residual laxity cases with grade I and II positive posterior drawer tests have been reported in the literature in PEANUT BUTTER pa